With Red Chests, you can re-open them each time you quit the game and start anew, while Typhon Dead Drops can only be looted once - so make sure you think hard about when you want to open these.

However, Mayhem Mode changes this, as it will bring all the chests up to your level along with all other loot and enemies in the region. With regards to level-locked regions, it's very important to note that both Red Chests (usually found after bosses or as bonus unlocked areas from side missions) as well as Typhon Dead Drops (crew challenges triangulated from finding recordings) are also locked to the region of that area (unless a region eventually upgrades over the course of the story).įor that reason you should always be exploring and looting chests in every region as you progress - as saving them for later will only lower the value of what's inside 5 levels later. Certain side missions will appear in areas before or after completing a main mission in that area, so be sure to look around and make sure you don't miss anything. Similarly, if you dash on ahead through main missions as fast as you can, you may start encountering enemies well above your own level, and all the loot they drop may also be unavailable to equip until you can catch up, which can really suck!īecause of this, it's worth your while to stop and smell the flowers - and by that we mean take on side missions, scope out challenges, and generally explore and do whatever you can before moving onto the next area.

This means that - for the most part - if you pass on a side mission and go back later, you'll likely find both the difficulty and rewards well below your level. The better question is: If that guy with the level 5 quest is offering level 5 loot, do we even want to help him at level 20?Īs you journey across the stars in Borderlands, you'll find out pretty early on that enemies will stick a certain level range when entering new areas and taking on missions.

Finally, your Artifact Slot will only unlock after taking on another Vault quest called Cold as the Grave, which is the 16th main mission.

Your Fourth Weapon Slot will unlock after completing the first vault mission in the main story, Beneath the Meridian, which is the 10th main mission.

Your Class Mod Slot will unlock after helping Rhys out on Promethea and defeating the boss and completing the quest Hostile Takeover, which is your 6th main mission.

Your Third Weapon Slot will unlock after leaving Pandora for the first time, completing the Taking Flight and Sanctuary quests at are your 4th and 5th main missions.

These unlocks are tied to completing story quests, so here's when you can expect to unlock them.

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